To run duply periodically you can add these options to your /etc/periodic.conf or /etc/periodic.conf.local Configuration Settings (with default values): backup_duply_enable="NO" enable duply backup backup_duply_profile="" default duply profile to use see duply usage backup_duply_command="bkp_status" default duply commands backup_duply_opt="" options passed to duply backup_duply_random="0" randomize backup time Add these lines to your /etc/crontab 10 3 * * * root periodic backup